Collagen regeneration, barrier repair and refined skin texture from within.
REJURAN® is a revolutionary skin rejuvenation treatment formulated with purified polynucleotides (PN) derived from wild salmon DNA. These DNA fragments stimulate skin repair, enhance collagen production, and improve skin barrier function, making REJURAN® one of the most effective treatments available for improving skin texture, elasticity, dark eye circles and overall tone.
Unlike traditional dermal fillers or hyaluronic acid-based boosters, REJURAN® works by stimulating your skin’s natural regenerative processes at the cellular level. It is particularly effective in treating the delicate under-eye area, where many other injectables cannot be safely used.
All REJURAN® treatments at The Skin Lab are performed by qualified medical professionals in a safe, clinical environment with personalised treatment planning.
Why We Love It
REJURAN® is one of the few injectable treatments clinically safe and effective for use under the eyes. It helps to:
– Smooth fine lines and crepey texture
– Brighten dark circles
– Firm and strengthen thin under-eye skin
– Improve hydration and skin resilience
A powerful option for treating:
– Fine lines and early skin laxity
– Acne scarring and large pores
– Dullness, dehydration, and uneven skin tone
– Fragile, thin or inflamed skin
– Post-inflammatory pigmentation and redness
Whether used on its own or as part of a broader skin program, REJURAN® helps restore skin function from within, resulting in smoother, firmer, healthier-looking skin.
What to expect
How does REJURAN® work?
REJURAN® contains highly purified polynucleotides (PN), extracted from wild salmon DNA using DOT™ (DNA Optimising Technology). These naturally biocompatible molecules stimulate fibroblast activity, improving collagen and elastin production, restoring hydration, and supporting the skin barrier. The result is smoother, firmer, clearer skin over time.
What areas can REJURAN® treat?
REJURAN® can be used on the:
– Face
– Neck
– Décolletage
– Under-eye area (ideal for fine lines, dark circles, and thin or fragile skin)
It’s also effective on scarred or inflamed areas where tissue needs repair and strengthening.
What happens during treatment?
A medical grade topical anesthetic is applied, followed by a series of shallow microinjections across the treatment area. The process is very comfortable and takes 30–45 minutes including numbing time. Small raised bumps may be visible immediately post-treatment and typically resolve within a few hours.
Is there downtime?
You may experience mild redness, swelling or pinpoint bruising, which usually resolves within 24–48 hours. Most clients return to normal activities the next day. Let your practitioner know if you’re prone to bruising.
How many sessions will I need?
Unlike conventional filler or laser, REJURAN® works by activating your skin’s ability to restore healthy collagen structure and increase skin elasticity. We recommend a course of 3 treatments, spaced 2–4 weeks apart. Maintenance every 6–12 months helps preserve and enhance results over time.
When will I see results?
Some clients notice early improvement in hydration and texture within 2–4 weeks. Collagen stimulation continues to build over several months, delivering firmer, more radiant skin and brighter under eyes.
What are Polynucleotides (PNs) in REJURAN®?
Polynucleotides (PNs) are highly purified DNA fragments derived from wild salmon, chosen for their natural compatibility with human skin. In REJURAN®, these molecules are used to support and enhance your skin’s own ability to heal and regenerate.
Rather than acting as a filler, PNs work by stimulating the skin’s natural repair systems, encouraging fibroblast activity leading to increased collagen production, improved tissue repair, and long-lasting benefits in skin strength, elasticity, and resilience.
Because PNs break down slowly within the skin, the regenerative effects are gradual, subtle, and sustained, helping to restore smoother, firmer, healthier-looking skin over time.
Can REJURAN® be combined with other treatments?
Yes. REJURAN® works beautifully alongside:
– Laser treatments: CO2, MOXI, PICO FX
– SkinPen or microneedling
– Anti-wrinkle injections
A customised treatment plan will be discussed during your consultation.
Is REJURAN® safe?
Yes. REJURAN® has been widely used across Asia and globally for more than a decade and is considered extremely safe when administered by trained professionals. It is well-tolerated by most skin types.
Who is not suitable for REJURAN®?
REJURAN® is considered suitable for most people. We don’t recommend treatment for those who are:
– Pregnant or breastfeeding
– Experiencing active skin infections or dermatitis
– Allergic to seafood or salmon-based products
We’ll assess your skin and medical history during your consultation to confirm suitability.
What’s the next step?
Book a consultation with one of our experienced doctors or nurses to determine if REJURAN® is the right treatment for your skin goals. A personalised plan will be tailored for your needs and if suitable treatment can be provided on the day.